| Intrigue | 1947 |
| Lady Jane Lady Jane Grey | 1985 |
| Room with a View Lucy Honeychurch | 1986 |
| Maurice Lady at Cricket Match | 1987 |
| Hazard of Hearts | 1987 |
| Mask | 1988 |
| Getting It Right Minerva Munday | 1989 |
| Francesco | 1989 |
| Hamlet Ophelia | 1990 |
| Howard's End Helen Schlegel | 1992 |
| Dancing Queen Pandora / Julie (as Helena Bonham-Carter) | 1993 |
| Mary Shelley's Frankenstein Elizabeth | 1994 |
| Mighty Aphrodite Amanda | 1995 |
| Margaret's Museum Margaret MacNeil | 1995 |
| Portraits Chinois Ada | 1996 |
| Dark Adapted Eye | 1996 |
| Keep the Aspidistra Flying Rosemary | 1997 |
| Merlin Morgan Le Fay | 1998 |
| Wings of the Dove Kate | 1998 |
| Fight Club Marla Singer | 1999 |
| Planet of the Apes Ari | 2001 |
| Novocaine Susan Ivey | 2002 |
| Big Fish Jenny/The Witch | 2003 |
| Lemony Snicket's A Series of Unfortunate Events Beatrice Baudelaire | 2004 |
| Charlie and the Chocolate Factory Mrs Bucket | 2005 |
| Wallace & Gromit: The Curse of the Were-Rabbit Lady Campanula Tottington | 2005 |
| Corpse Bride Voice: Corpse Bride | 2005 |
| Conversations with Other Women Woman | 2005 |
| Sweeney Todd: The Demon Barber of Fleet Mrs Lovett | 2007 |
| Harry Potter and the Order of the Phoenix Bellatrix Lestrange | 2007 |
| Harry Potter and the Half-Blood Prince Bellatrix Lestrange | 2009 |
| Terminator Salvation Serena | 2009 |
| Enid Blyton Enid Blyton | 2009 |
| Gruffalo Mother Squirrel | 2009 |
| Alice in Wonderland The Red Queen | 2010 |
| King's Speech Queen Elizabeth | 2010 |
| Harry Potter and the Deathly Hallows Part 1 Bellatrix Lestrange | 2010 |
| Harry Potter and the Deathly Hallows Part 2 Bellatrix Lestrange | 2011 |
| Gruffalo's Child Mother Squirrel | 2011 |
| Dark Shadows Dr. Julia Hoffman | 2012 |
| Les Misérables Madame Thénardier | 2012 |
| Lone Ranger Red Harrington | 2013 |
| Young and Prodigious T.S. Spivet Dr. Clair, T.S. Spivet's Mother | 2013 |
| Young and Prodigious T.S. Spivet Dr. Clair, T.S. Spivet's Mother | 2013 |
| Young and Prodigious T.S. Spivet Dr. Clair, T.S. Spivet's Mother | 2013 |
| Young and Prodigious T.S. Spivet Dr. Clair, T.S. Spivet's Mother | 2013 |
| Young and Prodigious T.S. Spivet Dr. Clair, T.S. Spivet's Mother | 2013 |
| Young and Prodigious T.S. Spivet Dr. Clair, T.S. Spivet's Mother | 2013 |
| Young and Prodigious T.S. Spivet Dr. Clair, T.S. Spivet's Mother | 2013 |
| Young and Prodigious T.S. Spivet Dr. Clair, T.S. Spivet's Mother | 2013 |
| Young and Prodigious T.S. Spivet Dr. Clair, T.S. Spivet's Mother | 2013 |
| Young and Prodigious T.S. Spivet Dr. Clair, T.S. Spivet's Mother | 2013 |
| Young and Prodigious T.S. Spivet Dr. Clair, T.S. Spivet's Mother | 2013 |
| Young and Prodigious T.S. Spivet Dr. Clair, T.S. Spivet's Mother | 2013 |
| Young and Prodigious T.S. Spivet Dr. Clair, T.S. Spivet's Mother | 2013 |
| Young and Prodigious T.S. Spivet Dr. Clair ( Photo Diary ) | 2013 |
| Young and Prodigious T.S. Spivet Dr. Clair, T.S. Spivet's Mother | 2013 |
| Young and Prodigious T.S. Spivet Dr. Clair, T.S. Spivet's Mother | 2013 |
| Young and Prodigious T.S. Spivet Dr. Clair, T.S. Spivet's Mother | 2013 |
| Young and Prodigious T.S. Spivet Dr. Clair, T.S. Spivet's Mother | 2013 |
| Cinderella Fairy Godmother | 2015 |
| Alice Through the Looking Glass Red Queen | 2016 |
| Sgt. Stubby: An American Hero Margaret Conroy (voice) | 2018 |
| Ocean's Eight Rose Weil | 2018 |
| Enola Holmes Eudoria Holmes | 2020 |
| One Life Babette Winton | 2023 |